Endocrine Abstracts

Introduction: Celiac disease (CD) is an autoimmune enteropathy, induced by dietary gluten in genetically predisposed subjects, which manifests itself, most often, by digestive signs but also extra-digestive signs, in particular failure to thrive (FTT), nevertheless it is necessary to remain vigilant with regard to a real associated somatotropic deficit.CASE: A 14-years-old male patient, followed for a celiac disease since the age of 6 years, under a stri...

Introduction: The discovery of thyroid cancer during surgery for another malignant disease of the upper aerodigestive tract is rare. We report the case of a man presenting squamous cell carcinoma (SCC) of the larynx associated with papillary thyroid carcinoma (PTC).Case presentation: A 68-year-old patient with history of cigarette smoking underwent total laryngectomy for laryngeal cancer associated with subglottic extension. Hemithyroidectomy on the lesi...

IntroductionThe coexistence of pulmonary adenocarcinoma and papillary carcinoma of the thyroid is a rare event. The relationship between these two cancers is still unclear; Far from being a coincidence, it’s most often attributed to a genetic mutation (of which that of BRAF’s the most common). The management must focus on the most aggressive carcinoma. In this case, it’s pulmonary adenocarcinoma since the latter carcinoma is known for its ...

<table Introduction: Neurofibromatosis type 1 is a multi-organ genetic disease, commonly occurring with variable severity. Pheochromocytoma is a rare manifestation in NF1, affecting 1-15% of NF1 patients according to studies.Case Report: We present 2 cases: - Patient 1: 28 years old, with personal history of café au lait spots, cutaneous and subcutaneous neurofibromas, axillary lentigines. Referred for endocrinology consultation due to an adrenal m...

Introduction: Allgrove syndrome or triple A syndrome is a rare genetic disorder of autosomal recessive inheritance combining in its complete form: esophageal achalasia, alacrymia and adrenal insufficiency.Observation: Patient aged 16, 3rd of 4 siblings from a consanguineous marriage, followed for allograve Sd with megaesophagus operated on in 2016, alacrymia with artificial tears and neurological impairment. As part of the follow-up of his pathology, an ...

Theassociation of primary hyperparathyroidism with autoimmune diseases is described very rarely in the literature so far. There are only few cases of immune-mediated hyperparathyroidism, associated with anti-calcium- sensing receptor autoantibodies, Recent epidemiological studies have shown that coeliac disease is more common than previously thought, with prevalence approaching 1%.Observation : A 47-year-old woman was diagnosed as having coeliac disease ...

Introduction: Prolactin adenomas are the most common pituitary tumors. The aim of treatment is to achieve normal prolactin levels in order to reduce tumor mass and restore the gonadotropic axis. Dopaminergic agonists, including cabergoline, are the standard treatment. But some adenomas can be resistant to this treatment and behave like aggressive tumors. We report the case of a macroprolactinoma resistant to cabergoline.Observation: 50-year-old female pa...

Introduction: Micro medullar, thyroid carcinoma is defined as a rare variant of MTC, with a size less than or equal to 1 cm, often incidentall, discovered.Observation: A 67-year-old patient with no medical history presented with two supraclavicular lymph nodes four years ago. A biopsy revealed metastatic tumor proliferation suggestive of a carcinomatous process. Immunohistochemistry confirmed cervical lymph node metastasis of MTC, and further testing sho...

Introduction: Acromegaly is a rare disease defined by the clinical expression of hyperfunction of the somatotropic axis with unchecked secretion of growth hormone. It has many complications, which is why early diagnosis is essential.ObservationWe report the case of a 47-year-old patient, with a history of chronic smoking and renal lithiasis operated on in 2018. His history of illness goes back 3 months to the onset of hypoacusis, which prompted the patient to consult an ENT sp...

Introduction: A toxic goiter is a goiter that functions autonomously, causing hypersecretion of thyroid hormones, and is almost always benign. We report here the case of a toxic goiter that revealed the presence of papillary thyroid carcinoma.Observation: Patient aged 68, with a history of arterial hypertension, followed for hyperthyroidism on a toxic goitre, with a thyroid scintigraphy showing an enlarged thyroid gland with intense uptake on the right s...